Gall bladder cancer

Epidemiology
About 5,000 cases per year in US
Female to male ratio is 2.5:1

Risk factors
Porcelain gall bladder
Anomalous bile duct anatomy
Gall bladder polyps
Smoking
EtOH
Obesity
Salmonella and Helicobacter biliis infection

Treatment
Surgery is curative but resectability rates are low
For T1a disease (usually found incidentally at cholecystectomy), no adjuvant therapy is needed
CRT often given adjuvantly