Histology varies by location
Anterior (4 T's): thymoma, thyroid (goiter), teratoma, lymphoma ("terrible lymphoma")
Middle: tracheal, esophageal, lymphoma/lymph node metastasis
Posterior: neurogenic tumors, mesenchymal tumors
The mediastinum is the most common site for extragonadal germ cell tumors
Cell type is the most important prognostic factor (non-germinomatous types fare worse)
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