Epidemiology
GBM represents about 5% of pediatric brain tumors
Brainstem gliomas ~10-15%
GBM is treated similarly to adults
Brainstem glioma
Dorsal, exophytic tumors are often indolent with a more favorable prognosis
Diffuse intrinsic brainstem glioma represents 70-80% of brainstem glioma, 2Y-OS ~20%
Failed regimens include dose escalation to 78Gy, multiple chemo regimens
XRT dose ~54Gy (to GTV + 1 - 1.5cm)
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